C. Victorri-Vigneau et al., British Journal of Clinical Pharmacology, 2007
- Titre traduit : Mise en évidence d’abus et de dépendance au Zolpidem : résultats des enquêtes du réseau français des CEIP
- Auteurs : C. Victorri-Vigneau, E. Dailly, G. Veyrac, P. Jolliet
- Résumé :
- Aim : To show that the nonbenzodiazepine hypnotic zolpidem has a higher abuse potential than previously documented.
- Method : An official enquiry was carried out by the Nantes Centre for Evaluation and Information on Pharmacodependence (CEIP). The authors made a review of literature and analysed French data corresponding to the drug’s postmarketing period collected by the CEIP network from 1993 to 2002.
- Results : The literature review yielded mixed results concerning the behavioural effects of zolpidem. Data from the CEIP and the 53 literature case reports highlight significant dependence and abuse potential of zolpidem.
- Conclusions : This study adds to the growing evidence that zolpidem has the potential for abuse and dependence. As a consequence, the French drug monograph has been modified by the French Health Authorities.
- Référence : Br J Clin Pharmacol. 2007 Aug;64(2):198-209.
- Liens :
- Résumé sur PubMed
- Texte intégral sur addictovigilance.fr + (accès restreint aux seuls Centres d’Addictovigilance)